Overexpression of KIT protein (CD117), the product of the c-kit gene, has been shown to have important prognostic and therapeutic implications for a number of malignant neoplasms. Previous studies ...
In order to investigate activation and internalization of c-kit we created a functional c-kit-EGFP chimera by inserting EYFP (enhanced yellow fluorescent protein) within the extracellular domain of ...
The c-Kit (CD117), receptor tyrosine kinase (RTK), and its ligand stem cell factor (SCF) are necessary for the development of embryos and the progression of human cancer. In gastrointestinal stromal ...
Taste is one of our most vital senses, shaping appetite, nutrition, and quality of life. Yet taste buds are fragile, relying heavily on the nerves that connect them to the brain. When those nerves are ...
Conditional survival nomogram after an R0 resection for gastric cancer. Background: Recently, c-kit exon 11 deletions, including codons 557 and/or 558, have been reported to predict a worse prognosis ...
Arcus Biosciences Inc. has disclosed mast/stem cell growth factor receptor Kit (KIT; c-Kit; CD117) inhibitors reported to be useful for the treatment of cancer, allergy, autoimmune, inflammatory, ...
Prognostic significance of tumor budding in resected pancreatic ductal adenocarcinoma (PDAC). This is an ASCO Meeting Abstract from the 2014 ASCO Annual Meeting I. This abstract does not include a ...
Enanta Pharmaceuticals Inc. has developed mast/stem cell growth factor receptor kit (KIT; c-KIT; CD117) inhibitors reported to be useful for the treatment of cancer, autoimmune disease, fibrosis, ...
c-Kit (CD117), a type III receptor tyrosine kinase (RTK), is involved in intracellular signaling. c-Kit and its ligand stem cell factor (SCF) are essential for embryonic development and the ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results
Feedback