The meticulous manufacturing and scale-up processes in pharmaceutical production reflect the industry’s unwavering dedication to upholding stringent standards throughout a drug or biological …

Five factors to consider when scaling up biologics production to meet global commercial output Bioreactor scale-up is a critical step in the production of biologics such as therapeutic proteins, …

Sep 10, 2024 · In biologics production, economies of scale can be achieved if the volume of the manufacturing train is increased by incorporating larger bioreactors and more efficient purification …

The successful development of biologics requires CMC development along with clinical development, including ensuring the readiness of manufacturing facilities for commercial production

May 6, 2025 · Scaling up protein manufacturing is a complex and critical step in the biopharmaceutical industry. Unlike small-scale production, large-scale manufacturing presents unique challenges …

Oct 2, 2020 · Bioreactor technology advances can offer seamless manufacturing scale-up and can reduce the timeline and cost of biologics production.

Feb 7, 2024 · A biologic manufacturing process typically involves scaling up of production from miniaturized, high-throughput bioreactors (15–250 mL) to bench-scale glass or single-use reactors …

Oct 17, 2024 · Conclusions Scaling drug product process development from the laboratory to commercial production requires a combination of technical expertise, robust planning, and a precise …

Mar 23, 2023 · Strategies for biologics production We have identified some of the strategies that can help firstly to accelerate the biologics production and scale-up processes and, secondly, to overcome …

Sep 12, 2024 · 🚀 Biologics manufacturers can scale production in three ways: scaling up, out, or down. 📈 Scaling up increases manufacturing volume but often needs significant investment. 🔄 Scaling out adds …